Yunhao Peng et al. recently published an article entitled “Modified trident-shaped electrode design for particle lateral position detection in microfluidic impedance flow cytometry” in Sensors and Actuators: A. Physical.
The article outlines the use of modified trident electrodes inside a microfluidic channel for the implementation of impedance flow cytometry for the detection of single particles and their lateral positions. The proposed design is displayed in the Figure below. The device is shown to detect impedance differences caused by less than 0.02% volume displacement. Additionally, using amplitude values, two different-sized microspheres were identified while showing an increase in signal amplitude with a smaller distance between electrodes. The full article can be found here: https://doi.org/10.1016/j.sna.2024.116062.
Figure. Illustration of the proposed trident-shaped electrode for the detection and measurement of lateral particle locations (y) of flowing particle/cells inside a microfluidic channel.