Brady Goenner et al. recently published “An open source platform to automate the design, verification, and manufacture of 3D printed microfluidic devices” in Scientific Reports.
Several barriers to widespread microfluidic adoption exist, including high initial fabrication costs and the labor-intensive development process. To address these barriers, a toolchain for the design, verification, and manufacturing of 3D printed microfluidic devices is presented. This work builds on existing electronic design automation (EDA) tools, yielding a toolchain that automatically lays out a microfluidic device from a library of components, simulates the device, and produces a 3D CAD file for manufacture via 3D printing. The process is validated by automatically designing and fabricating a calcium quantification assay. The full article can be found at https://doi.org/10.1038/s41598-025-15976-9.