Project: Microscale Cyclical Electrical Field Flow Fractionation

I am studying differential electrokinetic mobility based separations of nanoparticles & biomolecules using a new technique in Field Flow Fractination (FFF) called Cyclical Electrical FFF (CyElFFF). Unlike in Normal ElFFF, in CyElFFF Gouy-Chapmann double layer is disturbed using cyclical electrical field which results in improved electrical field (from 3% to 25% and more). This advantage is utilized in separating nanoparticles/biomolecules based on their electrophoretic mobilities. My research focusses on understanding and applying this method in miniaturization of CyElFFF. So far, apart from modeling, I am successful in improving fabrication and design of micro-CyElFFF and showing basic particle separation from a binary particle mixture. An optimized micro-CyElFFF system will be a good alternative technology for electrophoresis and general sample preparation methods based on separations.

Past Project: Microscale Platelet Analyzer

Publications:

Ameya S. Kantak, Bruce K. Gale , Yuri Lvov , Steven A. Jones , “Platelet Function Analyzer: Shear Activation of Platelets in Microchannels,” Biomedical Microdevices, Vol. 5, pp. 207-215, September, 2003.

Ameya S Kantak, Srinivas Merugu, Bruce K Gale, “Microfabricated Cyclical Electrical Field Flow Fractionation,” in Proc. of MicroTAS 2003, Squaw Valley, California, October 5-9, 2003.

Ameya Kantak and Bruce K. Gale, “Microscale Cyclical Electrical Field Flow Fractionation,” in Proc. Of the 11th International Symposium on Field Flow Fractionation, Cleveland, OH, October 7-10, 2003.

Ameya Kantak, Himanshu Sant, Bruce K. Gale, David K. Mills, Yuri Lvov, and Steve Jones, “A Microfabricated Platelet Analyzer,” in Proc. Smalltalk 2001, San Diego, CA, August 27-31, 2001.

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